Increased oxidative stress is associated with insulin resistance and infertility in polycystic ovary syndrome

Polycystic Ovary Syndrome: Insulin Resistance, Infertility, and Treatment

Serum betatrophin levels are increased and associated with insulin resistance in patients with polycystic ovary syndrome

Objective Betatrophin is a newly identified circulating protein that is significantly associated with type 2 diabetes mellitus (T2DM), adiposity, and metabolic syndrome. The aim of this study was to investigate whether betatrophin levels and polycystic ovary syndrome (PCOS) were associated. Methods Circulating betatrophin levels were measured in 162 patients with PCOS and 156 matched control fe...

High Serum Ferritin Concentrations in Polycystic Ovary Syndrome Is Not Related to Insulin Resistance

OBJECTIVE: Some data are available on the association between components of the insulin resistance syndrome and serum ferritin. Insulin resistance is observed in patients with polycystic ovary syndrome (PCOS) We hypothesize that body iron stores might be increased in these women. MATERIALS AND METHODS: Two hundred and six people (103 PCOS patients and 103 healthy women who were matched for a...

Role of Oxidative Stress in Polycystic Ovary Syndrome

Introduction: Polycystic ovary syndrome is one of the most common causes of infertility. 6 to 8 percent of women of childbearing age have this endocrine disorder. Biochemical abnormalities in these patients lead to imbalance of female hormones and increased androgens, which can have consequences such as menstrual cycle disorder, hirsutism, acne vulgaris and androgenic alopecia. Despite the long...

Insulin Resistance and Polycystic Ovary Syndrome.

BACKGROUND Insulin resistance and the associated compensatory hyperinsulinemia are common findings in women with PCOS, and may play a key role in this condition. METHODS In this article, we focused on the significance of insulin resistance in PCOS, reviewing the available literature on epidemiology, pathogenesis, pathophysiology and treatment of this condition. RESULTS It has been estimated...